Publications
Recent publications based on research conducted by Yale Stress Center investigators include:
Hyman, S.M., Paliwal, P., & Sinha, R. (2007) Child maltreatment, perceived stress, and stress-related coping in recently abstinent cocaine dependent adults. Psychology of Addictive Behaviors, 21(2), 233-238.
McKee SM, Carroll, KM, Sinha, R, Robinson, JE, Nich, C, Cavallo, D, O’Malley, SS (2007) Enhancing the Effectiveness of Brief Cognitive Behavioral Therapy for Cocaine Abuse or Dependence Use with Motivational Interviewing Techniques, Drug and Alcohol Dependence, 91(1):97-101
Sinha R (2007) The role of stress in addiction relapse. Current Psychiatry Reports, Vol 9(5), 388-395.
Li CSR, Yan P, Bergquist K, Sinha R (2007). Greater activation of the "Default" brain regions predicts stop signal errors. Neuroimage 38(3):640-8.
Li, C-SR, Huang, C, Yan P, Bhagawar Z, Milivojevic, V, Sinha, R (2008). Neural correlates of impulse control during stop signal inhibition in cocaine dependent men. Neuropsychopharmacology (Epub, Sept 30, 2007 online)
Hyman SM, Paliwal P, Chaplin T, Mazure C, Bergquist KT, Rounsaville BJ, Sinha R, (2008). Childhood trauma predicts more severe cocaine relapse outcomes in women compared to men. Drug and Alcohol Dependence, Vol 92, 208-216.
Paliwal P, Hyman SM, Sinha R (2008). Craving predicts time to cocaine relapse: Further validation of the Now and Brief Versions of the Cocaine Craving Questionnaire. Drug and Alcohol Dependence, Vol 93(3), March, 252-259.
Li, C-SR, Sinha R (2008). Inhibitory control and emotional stress regulation: Neuroimaging evidence for frontal-limbic dysfunction in psycho-stimulant addiction. Neuroscience & Biobehavioral Reviews, 32(3):581-97
Li, C-SR, Yan P, Huang, C, Paliwal P, Constable RT, Sinha, R (2008). Neural correlates of post-error slowing during a stop signal task: A functional magnetic resonance imaging study. Journal of Cognitive Neuroscience, Jan 22 (epub)
Fox HC, Sinha R (2008). Sex differences in stress responses in cocaine and alcohol dependent individuals: Implications for gender specific treatment development. Harvard Review of Psychiatry (in press)
Sinha R (2008). Stress increases addiction vulnerability and relapse. Annals of the New York Academy of Sciences: Addiction Reviews
Chaplin, TM, Hong KA, Bergquist K, Sinha R (2008). Gender differences in response to emotional stress: An assessment across subjective, behavioral and physiological domains. Alcoholism: Clinical and Experimental Research (accepted).
Potenza MN, Hong K, Lacadie CM, BS, Fulbright RK, Li C-SR, Bergquist KL, Sinha R (2008). Neural Correlates of Stress-Induced and Cue-Induced Craving: Influences of Gender and Cocaine Dependence. Archives of General Psychiatry (under review).
Husky MM, Mazure CM, Paliwal P, McKee SA (2008). Gender differences in the comorbidity of smoking behavior and major depression. Drug Alcohol Depend. Jan 11;93(1-2):176-9.
Toll BA, Salovey P, O'Malley SS, Mazure CM, Latimer A, McKee SA (2008).Message framing for smoking cessation: the interaction of risk perceptions and gender. Nicotine Tob Res. Jan;10(1):195-200.
Cosgrove KP, Mitsis EM, Bois F, Frohlich E, Tamagnan GD, Krantzler E, Perry E,
Maciejewski PK, Epperson CN, Allen S, O'malley S, Mazure CM, Seibyl JP, van Dyck
CH, Staley JK (2007). 123I-5-IA-85380 SPECT imaging of nicotinic acetylcholine receptor availability in nonsmokers: effects of sex and menstrual phase. J Nucl Med. 2007 Oct;48(10):1633-40.
Cosgrove KP, Mazure CM, Staley JK (2007). Evolving knowledge of sex differences in brain structure, function, and chemistry. Biol Psychiatry. Oct 15;62(8):847-55.
Morgan PT, Paliwal P, Malison RT, Sinha R (2008). Gender differences in sleep and sleep-dependent learning in abstinent cocaine users. Psychopharmacology (under revision)
Fox HC, Sinha R (2007). Stress, neuroendocrine responses and addiction in women. In Brady KT, Back SE, Greenfield SF (Eds.) Women and Addiction: A Comprehensive Textbook, Guilford Press.
Sinha R (2008). Cause of substance abuse: Stress. In Carson-DeWitt R (Ed.), Encyclopedia of Drugs, Alcohol and Addictive Behaviors (revised edition), MacMillan Reference USA, in press
O’Malley SS, Sinha R, Grilo C, Wu, R, McKee, SM, Capone S, Rounsaville RJ, O’Connor P, Farren C ( 2007). Naltrexone and cognitive behavioral coping skills therapy for the treatment of alcohol drinking and eating disorder features in alcohol-dependent women: a randomized controlled trial. Alcoholism: Clinical and Experimental Research, Apr;31(4):625-34.
Fox HC, Axelrod SR, Paliwal P, Sleeper J, Sinha R (2007). Difficulties in emotion regulation and impulse control during cocaine abstinence. Drug and Alcohol Dependence, (Feb 2, epub, ahead of print)
Kelly MM, Tyrka AR, Anderson GM, Price LH, Carpenter LL. Sex differences in emotional and physiological responses to the Trier Social Stress Test. Journal of Behavior Therapy & Experimental Psychiatry. 39:87-98, 2008
Carpenter LL, Carvalho JP, Tyrka AR, Wier LM, Mello AF, Mello MF, Anderson GM, Wilkinson CW, Price LH. Decreased adrenocorticotropic hormone and cortisol responses to stress in healthy adults reporting significant childhood maltreatment. Biological Psychiatry. 62:1080-7, 2007
Fox HC, Sinha R (2008). Sex differences in the neurobiology of addiction. 3rd International
Congress on Womens Mental Health, 17 -20 March, Melbourne.
Chaplin, T. M., Fahy, T., Sinha, R., & Mayes, L. (2007). Young children's emotional arousal and self-regulation in a frustrating task: Effects of gender and prenatal cocaine exposure. Journal of Women's Health, 16(8), 1114
Potenza, M., Bergquist, K., Milovojevic, V., Lacadie, C. M., Rajeevan, N., Li, C. S., et al. (2007). Sex differences in the neural correlates of stress and craving in cocaine dependence. Journal of Women's Health, 16(8), 1108.

Dr. Rajita Sinha, director of the Yale Stress Center, talks about the interplay of stress, self-control and problems with alcohol, tobacco and food addiction. You can