Publications & Media - Publications
| Arnsten AFT, Mazure C, Sinha R. This is your brain in meltdown. Scientific American, 2012, April, 48-53. |
| Rudenga KJ, Sinha R, Small DM. Acute stress potentiates brain response to milkshake as a function of body weight and chronic stress. Int J Obes (Lond). 2012 Mar 20. doi: 10.1038/ijo.2012.39. [Epub ahead of print] PubMed PMID: 22430303. |
| Potenza MN, Hong KI, Lacadie CM, Fulbright RK, Tuit KL, Sinha R. Neural Correlates of Stress-Induced and Cue-Induced Drug Craving: Influences of Sex and Cocaine Dependence. Am J Psychiatry. 2012 Jan 31. [Epub ahead of print] PubMed PMID: 22294257. |
| Fox H, Seo D, Tuit K, Hansen J, Kimmerling A, Morgan PT, Sinha R. Guanfacine effects on stress, drug craving and prefrontal activation in cocaine dependent individuals: preliminary findings. J Psychopharmacol. 2012 Feb 1. [Epub ahead of print] PubMed PMID: 22234929. |
| Ansell EB, Rando K, Tuit K, Guarnaccia J, Sinha R. Cumulative Adversity and Smaller Gray Matter Volume in Medial Prefrontal, Anterior Cingulate, and Insula Regions. Biol Psychiatry. 2012 Jan 2. [Epub ahead of print] PubMed PMID: 22218286. |
| Edmiston EE, Wang F, Mazure CM, Guiney J, Sinha R, Mayes LC, Blumberg HP. Corticostriatal-limbic gray matter morphology in adolescents with self-reported exposure to childhood maltreatment. Arch Pediatr Adolesc Med. 2011 Dec;165(12):1069-77. PubMed PMID: 22147775. |
| Xu J, Li Y, Lin H, Sinha R, Potenza MN. Body mass index correlates negatively with white matter integrity in the fornix and corpus callosum: A diffusion tensor imaging study. Hum Brain Mapp. 2011 Dec 3. doi: 10.1002/hbm.21491. [Epub ahead of print] PubMed PMID: 22139809. |
| Spann MN, Mayes LC, Kalmar JH, Guiney J, Womer FY, Pittman B, Mazure CM, Sinha R, Blumberg HP. Childhood abuse and neglect and cognitive flexibility in adolescents. Child Neuropsychol. 2011 Sep 26. [Epub ahead of print] PubMed PMID: 21942637. |
| Ashare RL, Sinha R, Lampert R, Weinberger AH, Anderson GM, Lavery ME, Yanagisawa K, McKee SA. Blunted vagal reactivity predicts stress-precipitated tobacco smoking. Psychopharmacology (Berl). 2011 Sep 21. [Epub ahead of print] PubMed PMID: 21938416; PubMed Central PMCID: PMC3260347. |
| Page KA, Seo D, Belfort-DeAguiar R, Lacadie C, Dzuira J, Naik S, Amarnath S, Constable RT, Sherwin RS, Sinha R. Circulating glucose levels modulate neural control of desire for high-calorie foods in humans. J Clin Invest. 2011 Oct 3;121(10):4161-9. doi: 10.1172/JCI57873. Epub 2011 Sep 19. PubMed PMID: 21926468; PubMed Central PMCID: PMC3195474. |
| Fox HC, Anderson GM, Tuit K, Hansen J, Kimmerling A, Siedlarz KM, Morgan PT, Sinha R. Prazosin effects on stress- and cue-induced craving and stress response in alcohol-dependent individuals: preliminary findings. Alcohol Clin Exp Res. 2012 Feb;36(2):351-60. doi: 10.1111/j.1530-0277.2011.01628.x. Epub 2011 Sep 15. PubMed PMID: 21919922; PubMed Central PMCID: PMC3243763. |
| Xu K, Hong KA, Zhou Z, Hauger RL, Goldman D, Sinha R. Genetic modulation of plasma NPY stress response is suppressed in substance abuse: Association with clinical outcomes. Psychoneuroendocrinology. 2011 Sep 12. [Epub ahead of print] PubMed PMID: 21917383; PubMed Central PMCID: PMC3252459. |
| Sinha R. New findings on biological factors predicting addiction relapse vulnerability. Curr Psychiatry Rep. 2011 Oct;13(5):398-405. Review. PubMed PMID: 21792580. |
| Sinha R. Modeling Relapse Situations in the Human Laboratory. Curr Top Behav Neurosci. 2011 Jul 17. [Epub ahead of print] PubMed PMID: 21769721. |
| D'Sa C, Fox HC, Hong AK, Dileone RJ, Sinha R. Increased serum brain-derived neurotrophic factor is predictive of cocaine relapse outcomes: a prospective study. Biol Psychiatry. 2011 Oct 5;70(8):706-11. Epub 2011 Jul 8. PubMed PMID: 21741029; PubMed Central PMCID: PMC3186871. |
| Sinha R, Fox HC, Hong KI, Hansen J, Tuit K, Kreek MJ. Effects of adrenal sensitivity, stress- and cue-induced craving, and anxiety on subsequent alcohol relapse and treatment outcomes. Arch Gen Psychiatry. 2011 Sep;68(9):942-52. doi: 10.1001/archgenpsychiatry.2011.49. Epub 2011 May 2. PubMed PMID: 21536969. |
| Sinha R, Shaham Y, Heilig M. Translational and reverse translational research on the role of stress in drug craving and relapse. Psychopharmacology (Berl). 2011 Nov;218(1):69-82. Epub 2011 Apr 15. PubMed PMID: 21494792; PubMed Central PMCID: PMC3192289. |
| Schepis TS, McFetridge A, Chaplin TM, Sinha R, Krishnan-Sarin S. A pilot examination of stress-related changes in impulsivity and risk taking as related to smoking status and cessation outcome in adolescents. Nicotine Tob Res. 2011 Jul;13(7):611-5. Epub 2011 Feb 28. PubMed PMID: 21357729; PubMed Central PMCID: PMC3129235. |
| Arnsten AF. Prefrontal cortical network connections: key site of vulnerability in stress and schizophrenia. Int J Dev Neurosci. 2011 May;29(3):215-23. Epub 2011 Feb 21. Review. PubMed PMID: 21345366; PubMed Central PMCID: PMC3115784. |
| Fox HC, Bergquist KL, Casey J, Hong KA, Sinha R. Selective cocaine-related difficulties in emotional intelligence: relationship to stress and impulse control. Am J Addict. 2011 Mar-Apr;20(2):151-60. doi: 10.1111/j.1521-0391.2010.00108.x. Epub 2010 Dec 28. PubMed PMID: 21314758; PubMed Central PMCID: PMC3166613. |
| Seo D, Jia Z, Lacadie CM, Tsou KA, Bergquist K, Sinha R. Sex differences in neural responses to stress and alcohol context cues. Hum Brain Mapp. 2011 Nov;32(11):1998-2013. doi: 10.1002/hbm.21165. Epub 2010 Dec 15. PubMed PMID: 21162046; PubMed Central PMCID: PMC3236497. |
| Rando K, Hong KI, Bhagwagar Z, Li CS, Bergquist K, Guarnaccia J, Sinha R. Association of frontal and posterior cortical gray matter volume with time to alcohol relapse: a prospective study. Am J Psychiatry. 2011 Feb;168(2):183-92. Epub 2010 Nov 15. PubMed PMID: 21078704. |
| Breese GR, Sinha R, Heilig M. Chronic alcohol neuroadaptation and stress contribute to susceptibility for alcohol craving and relapse. Pharmacol Ther. 2011 Feb;129(2):149-71. Epub 2010 Oct 15. Review. PubMed PMID: 20951730; PubMed Central PMCID: PMC3026093. |
| Chaplin TM, Freiburger MB, Mayes LC, Sinha R. Prenatal cocaine exposure, gender, and adolescent stress response: a prospective longitudinal study. Neurotoxicol Teratol. 2010 Nov-Dec;32(6):595-604. Epub 2010 Sep 17. PubMed PMID: 20826209; PubMed Central PMCID: PMC2983086. |
| McKee SA, Sinha R, Weinberger AH, Sofuoglu M, Harrison EL, Lavery M, Wanzer J. Stress decreases the ability to resist smoking and potentiates smoking intensity and reward. J Psychopharmacol. 2011 Apr;25(4):490-502. Epub 2010 Sep 3. PubMed PMID: 20817750. |
| Blanton RE, Chaplin TM, Sinha R. Sex differences in the correlation of emotional control and amygdala volumes in adolescents. Neuroreport. 2010 Oct 6;21(14):953-7. PubMed PMID: 20729768. |
| Chaplin TM, Hong K, Fox HC, Siedlarz KM, Bergquist K, Sinha R. Behavioral arousal in response to stress and drug cue in alcohol and cocaine addicted individuals versus healthy controls. Hum Psychopharmacol. 2010 Jul;25(5):368-76. PubMed PMID: 20589926; PubMed Central PMCID: PMC2917911. |
| Chaplin TM, Casey J, Sinha R, Mayes LC. Gender differences in caregiver emotion socialization of low-income toddlers. New Dir Child Adolesc Dev. 2010 Summer;2010(128):11-27. PubMed PMID: 20552657; PubMed Central PMCID: PMC2917975. |
| Bergquist KL, Fox HC, Sinha R. Self-reports of interoceptive responses during stress and drug cue-related experiences in cocaine- and alcohol-dependent individuals. Exp Clin Psychopharmacol. 2010 Jun;18(3):229-37. PubMed PMID: 20545387. |
| Fox HC, Bergquist KL, Peihua G, Rajita S. Interactive effects of cumulative stress and impulsivity on alcohol consumption. Alcohol Clin Exp Res. 2010 Aug;34(8):1376-85. Epub 2010 May 17. PubMed PMID: 20491738. |
| Hu J, Henry S, Gallezot JD, Ropchan J, Neumaier JF, Potenza MN, Sinha R, Krystal JH, Huang Y, Ding YS, Carson RE, Neumeister A. Serotonin 1B receptor imaging in alcohol dependence. Biol Psychiatry. 2010 May 1;67(9):800-3. Epub 2010 Feb 20. PubMed PMID: 20172504; PubMed Central PMCID: PMC3112181. |
| Brewer JA, Sinha R, Chen JA, Michalsen RN, Babuscio TA, Nich C, Grier A, Bergquist KL, Reis DL, Potenza MN, Carroll KM, Rounsaville BJ. Mindfulness training and stress reactivity in substance abuse: results from a randomized, controlled stage I pilot study. Subst Abus. 2009 Oct-Dec;30(4):306-17. PubMed PMID: 19904666; PubMed Central PMCID: PMC3045038. |
| Fox HC, Hong KI, Siedlarz KM, Bergquist K, Anderson G, Kreek MJ, Sinha R. Sex-specific dissociations in autonomic and HPA responses to stress and cues in alcohol-dependent patients with cocaine abuse. Alcohol Alcohol. 2009 Nov-Dec;44(6):575-85. Epub 2009 Sep 30. PubMed PMID: 19793926; PubMed Central PMCID: PMC2781765. |
| Sinha R. Stress and addiction: a dynamic interplay of genes, environment, and drug intake. Biol Psychiatry. 2009 Jul 15;66(2):100-1. PubMed PMID: 19555787; PubMed Central PMCID: PMC2730917. |
| Arnsten AF. Stress signalling pathways that impair prefrontal cortex structure and function. Nat Rev Neurosci. 2009 Jun;10(6):410-22. Review. PubMed PMID: 19455173; PubMed Central PMCID: PMC2907136. |
| Chaplin TM, Fahy T, Sinha R, Mayes LC. Emotional arousal in cocaine exposed toddlers: prediction of behavior problems. Neurotoxicol Teratol. 2009 Sep-Oct;31(5):275-82. Epub 2009 May 21. PubMed PMID: 19465113; PubMed Central PMCID: PMC2743887. |
| Fox HC, Jackson ED, Sinha R. Elevated cortisol and learning and memory deficits in cocaine dependent individuals: relationship to relapse outcomes. Psychoneuroendocrinology. 2009 Sep;34(8):1198-207. Epub 2009 Apr 16. PubMed PMID: 19375236; PubMed Central PMCID: PMC2746363. |
| Fox HC, Sinha R. Sex differences in drug-related stress-system changes: implications for treatment in substance-abusing women. Harv Rev Psychiatry. 2009;17(2):103-19. PubMed PMID: 19373619; PubMed Central PMCID: PMC2746371. |
| Mangieri RA, Hong KI, Piomelli D, Sinha R. An endocannabinoid signal associated with desire for alcohol is suppressed in recently abstinent alcoholics. Psychopharmacology (Berl). 2009 Jul;205(1):63-72. Epub 2009 Apr 3. PubMed PMID: 19343330; PubMed Central PMCID: PMC2715164. |
| Sinha R. Chronic stress, drug use, and vulnerability to addiction. Ann N Y Acad Sci. 2008 Oct;1141:105-30. Review. PubMed PMID: 18991954; PubMed Central PMCID: PMC2732004. |
| Sinha R. Modeling stress and drug craving in the laboratory: implications for addiction treatment development. Addict Biol. 2009 Jan;14(1):84-98. Epub 2008 Oct 20. Review. PubMed PMID: 18945295; PubMed Central PMCID: PMC2734447. |
| Sinha R, Fox HC, Hong KA, Bergquist K, Bhagwagar Z, Siedlarz KM. Enhanced negative emotion and alcohol craving, and altered physiological responses following stress and cue exposure in alcohol dependent individuals. Neuropsychopharmacology. 2009 Apr;34(5):1198-208. Epub 2008 Jun 18. PubMed PMID: 18563062; PubMed Central PMCID: PMC2734452. |
| Chaplin TM, Hong K, Bergquist K, Sinha R. Gender differences in response to emotional stress: an assessment across subjective, behavioral, and physiological domains and relations to alcohol craving. Alcohol Clin Exp Res. 2008 Jul;32(7):1242-50. PubMed PMID: 18482163; PubMed Central PMCID: PMC2575018. |
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